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1.
New Zealand Medical Journal ; 134(1537):28-43, 2021.
Article in English | MEDLINE | ID: covidwho-1303147

ABSTRACT

AIMS: We aim to quantify differences in clinical outcomes from COVID-19 infection in Aotearoa New Zealand by ethnicity and with a focus on risk of hospitalisation. METHODS: We used data on age, ethnicity, deprivation index, pre-existing health conditions and clinical outcomes on 1,829 COVID-19 cases reported in New Zealand. We used a logistic regression model to calculate odds ratios for the risk of hospitalisation by ethnicity. We also considered length of hospital stay and risk of fatality. RESULTS: After controlling for age and pre-existing conditions, we found that Maori have 2.50 times greater odds of hospitalisation (95% CI 1.39-4.51) than non-Maori non-Pacific people. Pacific people have three times greater odds (95% CI 1.75-5.33). CONCLUSIONS: Structural inequities and systemic racism in the healthcare system mean that Maori and Pacific communities face a much greater health burden from COVID-19. Older people and those with pre-existing health conditions are also at greater risk. This should inform future policy decisions including prioritising groups for vaccination.

2.
PLoS One ; 16(6): e0252499, 2021.
Article in English | MEDLINE | ID: covidwho-1256040

ABSTRACT

Models of contact tracing often over-simplify the effects of quarantine and isolation on disease transmission. We develop a model that allows us to investigate the importance of these factors in reducing the effective reproduction number. We show that the reduction in onward transmission during quarantine and isolation has a bigger effect than tracing coverage on the reproduction number. We also show that intuitively reasonable contact tracing performance indicators, such as the proportion of contacts quarantined before symptom onset, are often not well correlated with the reproduction number. We conclude that provision of support systems to enable people to quarantine and isolate effectively is crucial to the success of contact tracing.


Subject(s)
COVID-19/transmission , Contact Tracing/methods , Basic Reproduction Number , COVID-19/metabolism , Contact Tracing/statistics & numerical data , Disease Outbreaks , Humans , Models, Theoretical , Patient Isolation , Quarantine/methods , Quarantine/psychology , SARS-CoV-2/genetics , SARS-CoV-2/pathogenicity , Social Isolation/psychology
3.
Math Med Biol ; 38(3): 299-313, 2021 08 15.
Article in English | MEDLINE | ID: covidwho-1232217

ABSTRACT

We use a stochastic branching process model, structured by age and level of healthcare access, to look at the heterogeneous spread of COVID-19 within a population. We examine the effect of control scenarios targeted at particular groups, such as school closures or social distancing by older people. Although we currently lack detailed empirical data about contact and infection rates between age groups and groups with different levels of healthcare access within New Zealand, these scenarios illustrate how such evidence could be used to inform specific interventions. We find that an increase in the transmission rates among children from reopening schools is unlikely to significantly increase the number of cases, unless this is accompanied by a change in adult behaviour. We also find that there is a risk of undetected outbreaks occurring in communities that have low access to healthcare and that are socially isolated from more privileged communities. The greater the degree of inequity and extent of social segregation, the longer it will take before any outbreaks are detected. A well-established evidence for health inequities, particularly in accessing primary healthcare and testing, indicates that Maori and Pacific peoples are at a higher risk of undetected outbreaks in Aotearoa New Zealand. This highlights the importance of ensuring that community needs for access to healthcare, including early proactive testing, rapid contact tracing and the ability to isolate, are being met equitably. Finally, these scenarios illustrate how information concerning contact and infection rates across different demographic groups may be useful in informing specific policy interventions.


Subject(s)
COVID-19/transmission , Healthcare Disparities , Models, Biological , Pandemics , SARS-CoV-2 , Adolescent , Adult , Age Factors , Aged , Aged, 80 and over , Basic Reproduction Number/statistics & numerical data , COVID-19/epidemiology , COVID-19/prevention & control , Child , Computer Simulation , Contact Tracing , Female , Health Services Accessibility/statistics & numerical data , Healthcare Disparities/statistics & numerical data , Humans , Male , Mathematical Concepts , Middle Aged , New Zealand/epidemiology , Pandemics/prevention & control , Pandemics/statistics & numerical data , Stochastic Processes , Young Adult
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